MECHANISTIC INSIGHT INTO THE INDUCTION OF LIVER TISSUE-RESIDENT MEMORY CD8+ T CELLS BY GLYCOLIPID-PEPTIDE VACCINATION

Mechanistic insight into the induction of liver tissue-resident memory CD8+ T cells by glycolipid-peptide vaccination

Summary: We recently demonstrated that vaccines comprising antigenic peptides conjugated to a glycolipid agonist, termed glycolipid-peptide (GLP) vaccines, efficiently generate substantial numbers of long-lived CD8+ liver-resident memory T (Trm) cells that are crucial for protection against malaria liver-stage infection.To understand the underlying

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The Compact Irradiator Modulus Designed for DNA Repair and Mutagenesis Studies in ISS Microgravity Environment Using UVA Emitted by Light-Emitting Diodes

This work presents the design and characteristics of a new compact ultraviolet (UV) irradiator used in a biological onboard space flight experiment.The experiment, called DRM, took place in the International Space Station research facility (ISS-13 expedition), during the Centenary Mission (Russian-Brazil) in March-April 2006.The DRM main objective

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